Early Pregnancy Maternal Hepatocyte Growth Factor and Risk of Gestational Diabetes

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Early Pregnancy Maternal Hepatocyte Growth Factor and Risk of Gestational Diabetes

AIMS We investigated associations of serum hepatocyte growth factor (HGF) with risk of gestational diabetes mellitus (GDM). We also examined whether pre-pregnancy overweight/obesity status or leisure-time physical activity (LTPA) modify these associations. METHODS In a nested case-control study (173 GDM cases and 187 controls) among participants of a pregnancy cohort, early pregnancy (16 week...

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Early screening of gestational diabetes mellitus using maternal hemoglobin A1C: Revision of current screening guidelines

Background: HbA1C has been a known predictor and diagnostic test for diabetes type 2. However, this test has not yet been widely studied in GDM and more importantly no cutoff point has been defined for HbA1C in GDM. We investigated the efficacy of screening during first and second trimester of pregnancy and defined appropriate cutoff points according to HbA1C and FBS for predicting maternal GDM...

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Risk of glucose intolerance and gestational diabetes mellitus in relation to maternal habitual snoring during early pregnancy

BACKGROUND Obstructive sleep apnea (OSA) or habitual snoring is known to be associated with impaired glucose tolerance and type 2 diabetes among both men and non-pregnant women. We examined the association of habitual snoring during early pregnancy with risk of impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM). METHODS A cohort of 1,579 women was interviewed during earl...

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Maternal Serum Heme-Oxygenase-1 (HO-1) Concentrations in Early Pregnancy and Subsequent Risk of Gestational Diabetes Mellitus

BACKGROUND Heme oxygenase-1 (HO-1) concentrations have been recently reported to be elevated in impaired glucose tolerance and type 2 diabetes mellitus (T2DM). However, no study has examined the association between HO-1 concentrations and gestational diabetes mellitus (GDM). METHODS In a case-control study, nested within a prospective cohort of pregnant women (186 GDM cases and 191 women who ...

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Decreased maternal circulating hepatocyte growth factor (HGF) concentrations in pregnancies with small for gestational age infants.

Our purpose was to evaluate whether maternal and fetal hepatocyte growth factor (HGF) concentrations in pregnancies with small for gestational age (SGA) infants are different from those in pregnancies with appropriate for gestational age (AGA) infants. Maternal and fetal circulating HGF concentrations were compared between 55 pregnancies with AGA infants and 16 pregnancies with SGA infants at b...

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ژورنال

عنوان ژورنال: British Journal of Medicine and Medical Research

سال: 2015

ISSN: 2231-0614

DOI: 10.9734/bjmmr/2015/18632